Science Lab
N1-171

Peneotide

N1's oligomeric technology that enables tissue penetration and intracellular delivery of oligonucleotides for gene therapy

Targeting Tumor Micro-environment

Penetide, a peptide-based transporter technology targeting tumor microenvironment, carries the drug and localizes at tumor and metastasis site by interacting with tumor microenvironment

Selective On-site Drug Release

Absotride's proprietary linker technology that is designed to cleave and release active parent drug after entering tumor cells. The release is dependent on the biological stimuli of intracellular and tumor microenvironment

Overcoming Multi-Drug Resistance

Penetide enables the parent drug to overcome drug resistance mediated by membrane-associated export transporters, such as ATP-binding cassette (ABC) transporter P-glycoprotein (Pgp). Pgp is known to over-express in over 60% of cancers, particularly in peritoneal cancers and blood-brain barrier